Tesamorelin is a growth-hormone-releasing analog that can increase IGF-1 levels in both men and women. Tesamorelin was approved for use in the United States as therapy to reduce excess abdominal fat. Tesamorelin is also being evaluated as therapy of insulin resistance, obesity and nonalcoholic fatty liver. Tesamorelin may also improve cognitive function for people with old age, and patients who suffer increase risk in Alzheimer’s disease due to mild cognitive impairment.